Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:06 AM
Ignite Modification Date:
2025-12-25 @ 1:06 AM
NCT ID:
NCT02196493
Eligibility Criteria:
Inclusion Criteria:
* Age 18 and over
* Male or female
* Non-smokers for 10 years and \<20 pack year equivalents in total
* Persistent productive cough for \> 3 months in duration
* Use of effective contraception Acceptable contraceptive methods include: established use of oral, injected or implanted hormonal methods; placement of an intrauterine device (IUD) or intrauterine system (IUS); condom or occlusive cap (diaphragm or cervical/vault caps) with spermicide; true abstinence (when this is in line with the preferred and usual lifestyle of the participant); or vasectomised partner.
Exclusion Criteria:
* History of obvious inhaled irritant exposure
* Evidence of primary or secondary immunodeficiency.
* Clinically important bronchiectasis on HRCT scan
* Prolonged QT interval on ECG or significant cardiac pathology prior to commencing azithromycin
* Abnormal LFT's (greater than 2x upper limit of normal)
* Hypersensitivity to azithromycin or any macrolide/ketolide antibiotic
* Pregnancy or intent to become pregnant during course of study
* Contra-indication to bronchoscopy (as per British Thoracic Society Guidelines)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT02196493
Study Brief:
Protocol Section:
NCT02196493