Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:08 PM
Ignite Modification Date:
2025-12-24 @ 2:08 PM
NCT ID:
NCT02076295
Eligibility Criteria:
Inclusion criteria:
* PD subjects (M/F, non-smoking, ≥ 50 years old, Hoehn \& Yahr stages 1-4)
* Normal control subjects (N=15, M/F, non-smoking, ≥ 50 years old)
Exclusion Criteria:
* Active smoking, use of other tobacco products, or use of nicotinic drugs such as nicotine patches or varenicline.
* Subjects with contra-indications to MR imaging, including pacemakers or claustrophobia.
* Evidence of large vessel stroke or mass lesion on MRI.
* Use of (anti-)cholinergic or neuroleptic drugs.
* Dementia or severe cognitive impairment confirmed by clinical and detailed neuropsychological assessment precluding safe study participation, performing study procedures, or unable to follow directions by study personnel.
* Evidence of atypical parkinsonism on neurological exam.
* Subjects limited by participation in research procedures involving ionizing radiation.
* Pregnancy (test within 48 hours of each PET session) or breastfeeding
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT02076295
Study Brief:
Protocol Section:
NCT02076295