Ignite Creation Date:
2024-05-05 @ 11:22 PM
Last Modification Date:
2024-10-26 @ 10:33 AM
Study NCT ID:
NCT01318889
Status:
UNKNOWN
Last Update Posted:
2011-07-06
First Post:
2011-03-08
Brief Title:
Dexpanthenol Mouthwash to Treat Oral Mucositis
Sponsor:
Shahid Beheshti University of Medical Sciences
Organization:
Shahid Beheshti University of Medical Sciences
Study Overview
Official Title:
Effects of Topical Dexpanthenol on Chemotherapy and Radiotherapy Induced Oral Mucositis
Status:
UNKNOWN
Status Verified Date:
2010-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Oral mucositis can be a significant problem for cancer patients It is typically associated with pain and increased risk of infection and can lead to impaired nutritional status and inadequate hydrationit can be seen in the patient population receiving high-dose head and neck radiation therapy 85-100 Topical dexpanthenol acts like a moisturizer improving stratum corneum hydration reducing transepidermal water loss and maintaining skin softness and elasticity The stimulation of epithelization granulation and mitigation of itching were the most prominent effects of formulations containing dexpanthenol The investigators suppose that dexpanthenol mouth wash may improve oral mucositis
Detailed Description:
Patients will be given a bottle of 5 Dexpanthenol mouthwash and they are asked to rinse 10 ml of it three times a day At the onset of mucositis and then for 4 subsequent weeks they will be examined to evaluate the condition of their oral mucosaBy the advent of mucositis stage 4 at any time during the 4 weeks of studythe patient would be outif any patient shows allergic reaction to dexpanthenolheshe would be out of study too
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None