Ignite Creation Date:
2024-05-05 @ 11:34 AM
Last Modification Date:
2024-10-26 @ 9:10 AM
Study NCT ID:
NCT00086554
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2004-07-02
Brief Title:
Collection of Specimens for Study of Inflammatory Bowel Disease
Sponsor:
National Institute of Allergy and Infectious Diseases NIAID
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Procurement of Clinical Specimens for Immunologic or Genetic Studies in Inflammatory Bowel Diseases
Status:
COMPLETED
Status Verified Date:
2010-01-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will collect tissue specimens to be used for research on inflammatory bowel disease The tissues will be used to explore why people get inflammatory bowel disease and to try to develop new treatments based on the study results Tissue from patients with IBD will be compared with that from patients who do not have the disease
Patients who undergo bowel surgery for inflammatory bowel disease IBD or another bowel disorder may be eligible for this study Patients with IBD must be at least 4 years of age those with another disorder must be 18 years of age or older
Participants undergo bowel surgery for their disease Some of the intestinal tissue removed during the surgery that is not needed for medical care such as for pathological examination is provided to researchers for study under this protocol In addition patients with IBD provide a blood sample for genetic testing Several genetic variations or mutations may increase the risk of developing IBD blood samples from patients may help identify these variations
Patients who undergo bowel surgery for inflammatory bowel disease IBD or another bowel disorder may be eligible for this study Patients with IBD must be at least 4 years of age those with another disorder must be 18 years of age or older
Participants undergo bowel surgery for their disease Some of the intestinal tissue removed during the surgery that is not needed for medical care such as for pathological examination is provided to researchers for study under this protocol In addition patients with IBD provide a blood sample for genetic testing Several genetic variations or mutations may increase the risk of developing IBD blood samples from patients may help identify these variations
Detailed Description:
Our ongoing natural history studies of the etiology and immune abnormalities of the group of diseases known collectively as the inflammatory bowel diseases require access to clinical samples of intestinal tissue as well as blood samples for genotyping This protocol provides a mechanism for procurement of intestinal samples obtained at the time of medically-indicated surgical procedures from patients with IBD or some other non-IBD diagnosis to act as a control group In addition it allows for the procurement of blood for DNA preparation as more IBD susceptibility genes are discovered and we further our work on association of genetic polymorphismsmutations with the phenotype and immune abnormalities observed in our IBD patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 04-I-0231 | None | None | None |