Ignite Creation Date:
2024-05-05 @ 11:35 AM
Last Modification Date:
2024-10-26 @ 9:10 AM
Study NCT ID:
NCT00081523
Status:
RECRUITING
Last Update Posted:
2024-07-09
First Post:
2004-04-15
Brief Title:
Natural History of Sickle Cell Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Studies of the Natural History of Sickle Cell Disease
Status:
RECRUITING
Status Verified Date:
2024-08-29
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is not a treatment protocol and no experimental treatments are involved Study participants may be seen as needed for clinical translational and basic research studies or as medically indicated Subjects will receive their general medical care outside the NIH and will be seen at our clinic or at CNHS with varying frequency Subjects may be seen for multiple visits Subjects may be asked to return for additional testing as needed Clinical care for patients with sickle cell disease will be provided as appropriate through the Sickle Cell Clinic and the inpatient clinical center
Detailed Description:
This protocol will permit the establishment of a repository of biospecimens from individuals affected with sickle cell disease to identify and evaluate underlying disease mechanisms and to facilitate understanding of the pathogenesis and natural history of vaso-occlusive painful crisis and other complications of the disease Patients will be evaluated with a medical history and physical examination and routine laboratory studies will be obtained as needed to assess diagnosis disease activity and disease complications and to monitor for treatment-related responses and toxicities This protocol may also provide for the continued storage and analysis of clinical and research data and biospecimens previously obtained from other NIH Institutional Review Board IRB-approved protocols with subject consent
Patients eligible for other research protocols will be offered an opportunity to participate in these studies after signed informed consent has been obtained Apart from such protocols any medical care or additional testsinvestigations recommended or provided to the patient will be consistent with routine standards of practice and will be provided in consultation with the patient s referring physician
Patients eligible for other research protocols will be offered an opportunity to participate in these studies after signed informed consent has been obtained Apart from such protocols any medical care or additional testsinvestigations recommended or provided to the patient will be consistent with routine standards of practice and will be provided in consultation with the patient s referring physician
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 04-H-0161 | None | None | None |