Ignite Creation Date:
2024-05-05 @ 10:00 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005557
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-12-07
First Post:
2000-05-25
Brief Title:
Epidemiology of Sleep-Disordered Breathing in Adults
Sponsor:
University of Wisconsin Madison
Organization:
University of Wisconsin Madison
Study Overview
Official Title:
Epidemiology of Sleep-Disordered Breathing in Adults
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To characterize the natural history and biologic spectrum of sleep disordered breathing SDB and other sleep problems and disorders and test hypotheses regarding the causes and consequences of SDB and other sleep problems and disorders
Detailed Description:
BACKGROUND
Recent research has shown that sleep disordered breathing SDB is much more common than previously thought While it is known that in clinic samples SDB is associated with hypertension cardiovascular disease and mortality little is known about the natural history of this disorder particularly in the general population nor about the causal role of known risk factors The knowledge obtained from the results of this study will help advance the field of sleep disorders medicine Information about longitudinal effects and causal relationships may be applied to clinical situations thus reducing the morbidity and mortality associated with this disorder
DESIGN NARRATIVE
In this longitudinal study follow-up polysomnography and other protocols are conducted on an established cohort of men and women age 30-60 years at the time of initial recruitment in 1989 currently enrolled in the Wisconsin Sleep Cohort Study The study aims to 1 describe the natural history of SDB across middle and older age 2 investigate associations of SDB with early and intermediate markers of cardiovascular dysfunction damage and cardiovascular disease 3 investigate the longitudinal association of SDB in accelerated cognitive decline 4 investigate the association of SDB and adverse sleep characteristics with age-related risk factors and outcomes
Recent research has shown that sleep disordered breathing SDB is much more common than previously thought While it is known that in clinic samples SDB is associated with hypertension cardiovascular disease and mortality little is known about the natural history of this disorder particularly in the general population nor about the causal role of known risk factors The knowledge obtained from the results of this study will help advance the field of sleep disorders medicine Information about longitudinal effects and causal relationships may be applied to clinical situations thus reducing the morbidity and mortality associated with this disorder
DESIGN NARRATIVE
In this longitudinal study follow-up polysomnography and other protocols are conducted on an established cohort of men and women age 30-60 years at the time of initial recruitment in 1989 currently enrolled in the Wisconsin Sleep Cohort Study The study aims to 1 describe the natural history of SDB across middle and older age 2 investigate associations of SDB with early and intermediate markers of cardiovascular dysfunction damage and cardiovascular disease 3 investigate the longitudinal association of SDB in accelerated cognitive decline 4 investigate the association of SDB and adverse sleep characteristics with age-related risk factors and outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| SMPHPOP HEALTH SCIPOP HLTH | OTHER | UW Madison | httpsreporternihgovquickSearchR01HL062252 |
| R01HL062252 | NIH | None | None |
| A538500 | OTHER | None | None |