Ignite Creation Date:
2024-05-06 @ 12:21 AM
Last Modification Date:
2024-10-26 @ 10:48 AM
Study NCT ID:
NCT01553708
Status:
COMPLETED
Last Update Posted:
2013-03-25
First Post:
2012-02-28
Brief Title:
Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound
Sponsor:
Chulalongkorn University
Organization:
Chulalongkorn University
Study Overview
Official Title:
The Clinical Efficacy of Epidermal Growth Factor With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream on Acceleration of Partial Thickness Burn Wound Healing
Status:
COMPLETED
Status Verified Date:
2013-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Partial thickness burn wounds are most likely to heal within 2-3 weeks mainly by mechanism of epithelialization However it depends on the depth of the wounds and patient condition Infection is one of the most common complications causing delay in wound healing which might affect to quality of patients life Generally the standard treatment of partial thickness burn wound is topical 1 silver sulfadiazine cream Previous studies had been reported the broad spectrum antimicrobial activity of silver sulfadiazine cream but it did not demonstrate the accelerating effect of wound healing Therefore the combination of substance which can promote wound healing to topical silver sulfadiazine cream might benefit for partial thickness burn wound treatment
The objective of this study was to compare the results of partial thickness burn wound treatment at burn unit Siriraj hospital with topical cream containing 1 silver sulfadiazine plus 6 epidermal growth factor EGF and 1 silver zinc sulfadiazine The demographic data age sex body surface area burn time of wound closure pain and itching dose and type of pain and itching medication adverse effect of topical medication some laboratory results and cost of expenses
This is the prospective double blinded randomize-controlled study The sample sizes were partial thickness burn wound patients who were treated at burn unit Siriraj hospital Patients were allocated into 2 groups receiving treatment with either topical silver sulfadiazine plus EGF or silver zinc sulfadiazine All parameter data were analyzed with repeated measure ANOVA and independent t-test
The objective of this study was to compare the results of partial thickness burn wound treatment at burn unit Siriraj hospital with topical cream containing 1 silver sulfadiazine plus 6 epidermal growth factor EGF and 1 silver zinc sulfadiazine The demographic data age sex body surface area burn time of wound closure pain and itching dose and type of pain and itching medication adverse effect of topical medication some laboratory results and cost of expenses
This is the prospective double blinded randomize-controlled study The sample sizes were partial thickness burn wound patients who were treated at burn unit Siriraj hospital Patients were allocated into 2 groups receiving treatment with either topical silver sulfadiazine plus EGF or silver zinc sulfadiazine All parameter data were analyzed with repeated measure ANOVA and independent t-test
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None