Ignite Creation Date:
2024-05-05 @ 11:41 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00101465
Status:
COMPLETED
Last Update Posted:
2013-07-03
First Post:
2005-01-10
Brief Title:
Partnership Programs for Reducing Cardiovascular Disparities in Native Hawaiians
Sponsor:
University of Hawaii
Organization:
University of Hawaii
Study Overview
Official Title:
Partnership Programs to Reduce Cardiovascular Disparities - Heart Failure Disparities in Native Hawaiians
Status:
COMPLETED
Status Verified Date:
2009-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to improve cardiovascular disease CVD outcomes in racial and ethnic minorities in Hawaii
Detailed Description:
BACKGROUND
While there has been great progress in reducing CVD morbidity and mortality in the US over the past 40 years some minority groups have not benefitted from this progress and continue to have lower life expectancy and higher CVD morbidity On average minorities have more limited access to medical care receive less aggressive care and receive fewer diagnostic and therapeutic cardiac procedures than non-minority populations Additionally most minority groups adhere poorly to prescribed medical regimens and often present to emergency departments rather than primary care physicians for complications of advanced chronic CVD conditions Thus research to reduce health disparities by improving CVD outcomes in minorities offers potential for a substantial positive impact on public health Academic medical centers and institutions that are capable of carrying out such research however often lack access to minority patients and have difficulty gaining the trust of those they are able to treat Minority communities often report greater satisfaction when receiving care from minority providers and are reluctant to receive treatment outside their minority healthcare serving systems
In general minorities have high rates of elevated cholesterol hypertension cigarette smoking obesity metabolic syndrome and diabetes Other behavioral environmental and occupational risk factors for cardiovascular diseases such as sleep problems are also common among minorties These risk factors all contribute to excess CVD morbidity and mortality Heart failure HF is also a major public health problem The impact of HF on minority populations such as Native Hawaiians and other Pacific peoples is unknown Native Hawaiians are known to have high rates of risk factors for HF and one of the highest rates of CVD mortality in the US The causes of minority health disparities are complex and are not understood completely Although evidence of genetic biologic and environmental factors is well documented poor outcomes are also attributed to incomplete treatment Such treatment may be due to limited access to health care or in some cases break-down of the medical system or failure of the physician andor patient to allow for optimal health care even when access is not impaired The complex interactions of behavior socio-economic status SES culture and ethnicity are important predictors of health outcomes and sources of health disparities Despite efforts to elucidate genetic and environmental risk factors and to promote cardiovascular health in high-risk populations trends in CVD outcomes suggest that CVD health disparities continue to widen
The Partnerships Program to Reduce Cardiovascular Health Disparities involves collaboration between research-intensive medical centers RIMCs that have a track record of NIH-supported research and patient care and minority healthcare serving systems MSSs that lack a strong research program Each Partnership Program will design and carry out multiple interdisciplinary research projects that investigate complex biologic behavioral and societal factors that contribute to CVD health disparities and facilitate clinical research within the MSS The aim will be to improve CVD outcomes and reduce health disparities Additionally each program will provide reciprocal educational and skills development programs to train investigators to conduct research that is aimed at reducing cardiovascular disparities thereby enhancing research opportunities and enriching cultural sensitivity and cardiovascular research capabilities at both institutions
The Request for Applications for Partnership Programs to Reduce Cardiovascular Disparities was released in September 2003 The awards were made in September 2004
DESIGN NARRATIVE
To address heart failure disparities among native Hawaiians and Pacific peoples a partnership program the HF Disparities Program HFD will be established between the Queen Emma Clinic QEC and the Department of Native Hawaiian Health Partners of the HFD Program include tha following MedStar Research Institute Oahu-based Community Health Centers CHCs and the Hawaii EXPORT Center an NIH-funded initiative addressing diabetes-associated disparities in native Hawaiians and Pacific peoples The HFD Program will address the following aims determine the reliability and validity of echocardiograms performed by community-based health workers compared to a professionally trained sonographer as the gold standard determine if a culturally competent educational program for heart failure reduces HF hospitalizations and mortality compared to usual care characterize ethnic differences in the HF syndrome in hospitalized native Hawaiians and Pacific peoples compared to Caucasians construct HF pedigrees using probands identified at the Queen Emma Clinic for a future HF linkage study in native Hawaiians and Pacific peoples educate community-based health workers to perform echocardiography scans for the detection of HF in a high risk population of native Hawaiians and Pacific peoples and train new investigators to conduct research focused on CVD disparities in general and HF in particular By achieving these aims the HFD Program will improve access to HF care at Community Health Centers that serve native Hawaiians and Pacific peoples fill a gap in knowledge of CVD disparities in native Hawaiians and Pacific peoples and provide a foundation for future studies on genetic determinants of HF
While there has been great progress in reducing CVD morbidity and mortality in the US over the past 40 years some minority groups have not benefitted from this progress and continue to have lower life expectancy and higher CVD morbidity On average minorities have more limited access to medical care receive less aggressive care and receive fewer diagnostic and therapeutic cardiac procedures than non-minority populations Additionally most minority groups adhere poorly to prescribed medical regimens and often present to emergency departments rather than primary care physicians for complications of advanced chronic CVD conditions Thus research to reduce health disparities by improving CVD outcomes in minorities offers potential for a substantial positive impact on public health Academic medical centers and institutions that are capable of carrying out such research however often lack access to minority patients and have difficulty gaining the trust of those they are able to treat Minority communities often report greater satisfaction when receiving care from minority providers and are reluctant to receive treatment outside their minority healthcare serving systems
In general minorities have high rates of elevated cholesterol hypertension cigarette smoking obesity metabolic syndrome and diabetes Other behavioral environmental and occupational risk factors for cardiovascular diseases such as sleep problems are also common among minorties These risk factors all contribute to excess CVD morbidity and mortality Heart failure HF is also a major public health problem The impact of HF on minority populations such as Native Hawaiians and other Pacific peoples is unknown Native Hawaiians are known to have high rates of risk factors for HF and one of the highest rates of CVD mortality in the US The causes of minority health disparities are complex and are not understood completely Although evidence of genetic biologic and environmental factors is well documented poor outcomes are also attributed to incomplete treatment Such treatment may be due to limited access to health care or in some cases break-down of the medical system or failure of the physician andor patient to allow for optimal health care even when access is not impaired The complex interactions of behavior socio-economic status SES culture and ethnicity are important predictors of health outcomes and sources of health disparities Despite efforts to elucidate genetic and environmental risk factors and to promote cardiovascular health in high-risk populations trends in CVD outcomes suggest that CVD health disparities continue to widen
The Partnerships Program to Reduce Cardiovascular Health Disparities involves collaboration between research-intensive medical centers RIMCs that have a track record of NIH-supported research and patient care and minority healthcare serving systems MSSs that lack a strong research program Each Partnership Program will design and carry out multiple interdisciplinary research projects that investigate complex biologic behavioral and societal factors that contribute to CVD health disparities and facilitate clinical research within the MSS The aim will be to improve CVD outcomes and reduce health disparities Additionally each program will provide reciprocal educational and skills development programs to train investigators to conduct research that is aimed at reducing cardiovascular disparities thereby enhancing research opportunities and enriching cultural sensitivity and cardiovascular research capabilities at both institutions
The Request for Applications for Partnership Programs to Reduce Cardiovascular Disparities was released in September 2003 The awards were made in September 2004
DESIGN NARRATIVE
To address heart failure disparities among native Hawaiians and Pacific peoples a partnership program the HF Disparities Program HFD will be established between the Queen Emma Clinic QEC and the Department of Native Hawaiian Health Partners of the HFD Program include tha following MedStar Research Institute Oahu-based Community Health Centers CHCs and the Hawaii EXPORT Center an NIH-funded initiative addressing diabetes-associated disparities in native Hawaiians and Pacific peoples The HFD Program will address the following aims determine the reliability and validity of echocardiograms performed by community-based health workers compared to a professionally trained sonographer as the gold standard determine if a culturally competent educational program for heart failure reduces HF hospitalizations and mortality compared to usual care characterize ethnic differences in the HF syndrome in hospitalized native Hawaiians and Pacific peoples compared to Caucasians construct HF pedigrees using probands identified at the Queen Emma Clinic for a future HF linkage study in native Hawaiians and Pacific peoples educate community-based health workers to perform echocardiography scans for the detection of HF in a high risk population of native Hawaiians and Pacific peoples and train new investigators to conduct research focused on CVD disparities in general and HF in particular By achieving these aims the HFD Program will improve access to HF care at Community Health Centers that serve native Hawaiians and Pacific peoples fill a gap in knowledge of CVD disparities in native Hawaiians and Pacific peoples and provide a foundation for future studies on genetic determinants of HF
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| U01HL079163 | NIH | None | httpsreporternihgovquickSearchU01HL079163 |