Ignite Creation Date:
2024-05-05 @ 11:41 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00102232
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2005-01-25
Brief Title:
Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers
Sponsor:
Wageningen Centre for Food Sciences
Organization:
Wageningen Centre for Food Sciences
Study Overview
Official Title:
Effect of Choline Supplemented as Phosphatidylcholine on Post-Methionine Loading and Fasting Concentrations of Plasma Homocysteine in Healthy Volunteers
Status:
COMPLETED
Status Verified Date:
2005-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether supplementation with phosphatidylcholine lowers plasma homocysteine concentrations in healthy men
Detailed Description:
A high homocysteine concentration is a potential risk for cardiovascular disease Plasma homocysteine concentrations can be lowered through betaine supplementation However effects of choline supplementation the precursor for betaine on plasma homocysteine concentrations in healthy humans are unknown If supplementation with choline or phosphatidylcholine the form in which choline occurs in foods lowers homocysteine concentrations then extra intake of these compounds may lower cardiovascular disease risk in humans
Comparison We compared the effects of supplementation with phosphatidylcholine to the effects of a placebo on fasting and post-methionine concentrations of plasma homocysteine in healthy men
Comparison We compared the effects of supplementation with phosphatidylcholine to the effects of a placebo on fasting and post-methionine concentrations of plasma homocysteine in healthy men
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None