Ignite Creation Date:
2024-05-05 @ 11:41 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00103805
Status:
COMPLETED
Last Update Posted:
2014-05-21
First Post:
2005-02-14
Brief Title:
Improved Language Acquisition With Levodopa
Sponsor:
University Hospital Muenster
Organization:
University Hospital Muenster
Study Overview
Official Title:
Improved Language Acquisition With Levodopa
Status:
COMPLETED
Status Verified Date:
2014-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether the non-daily administration of levodopa is effective in boosting semantic language acquisition in healthy subjects
Detailed Description:
Our prior work using a between-subject design shows that daily administration of d-amphetamine or the dopamine precursor levodopa over the course of five days markedly improves word learning success in healthy subjects In this randomized placebo-controlled double-blind clinical trial we probe whether the effect can be replicated using a within-subject design with administration of levodopa and placebo on alternate days for a total period of 10 days
The expected scientific results will strengthen the basis for transferring neuromodulatory interventions from the laboratory to stroke patients with language dysfunctions Because of the heterogeneity of stroke patients only a within-subject design can be used to probe the effects of pharmacological adjuncts to language therapy
The expected scientific results will strengthen the basis for transferring neuromodulatory interventions from the laboratory to stroke patients with language dysfunctions Because of the heterogeneity of stroke patients only a within-subject design can be used to probe the effects of pharmacological adjuncts to language therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None