Ignite Creation Date:
2025-12-24 @ 2:39 PM
Ignite Modification Date:
2025-12-24 @ 2:39 PM
Study NCT ID:
NCT03842059
Status:
UNKNOWN
Last Update Posted:
2019-02-15
First Post:
2019-02-13
Is Possible Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Computer-aided Detection for Colonoscopy
Sponsor:
Tri-Service General Hospital
Organization:
Study Overview
Official Title:
Computer-aided Detection With Deep Learning for Colorectal Adenoma During Colonoscopic Examination
Status:
UNKNOWN
Status Verified Date:
2019-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We developed an artificial intelligent computer system with a deep neural network to analyze real-time video signals from the endoscopy station. This randomised controlled trial compared adenoma detection rate between computer-assisted colonoscopy and standard colonoscopy.
Detailed Description:
Colonoscopy is a primary screening and follow-up tool to detect colorectal cancer, a third leading cause of cancer death in Taiwan. Most colorectal cancers (CRCs) arise from preexisting adenomas, and the adenoma-carcinoma sequence offers an opportunity for the screening and prevention of CRCs. The removal of adenomatous polyps can lower the incidence of CRCs and result in reduced motality from CRCs. The adenoma detection rate, the proportion of screening colonoscopies performed by a endoscopist that detect at least one colorectal adenoma or adenocarcinoma, has been recommended as a quality indicator. The adenoma detection rate was inversely associated with the risks of interval colorectal cancer, advanced-stage interval cancer, and fatal interval cancer. However, adenoma detection rates vary widely among endoscopists in both academic and community settings. Polyp miss rates as high as 20% have been reported for high definition resolution colonoscopy. An improvement in adenoma detection rate at screening colonoscopy, translates into reduced risks of interval colorectal cancer and colorectal cancer death. Computer-aided detection of polyps might assist endoscopists to reduce the miss rate and enhance screening performance during colonoscopy. Computer-aided diagnosis and computer-aided detection are computerized systems that learn and inference in medical fields. Computer-aided diagnosis has been developed in colon polyp classification.
Computer-assisted image analysis has the potential to further aid adenoma detection but has remained underdeveloped. A notable benefit of such a system is that no alteration of the colonoscope or procedure is necessary. Machine learning with a deep neural network has been successfully applied to many areas of science and technology, such as object recognition and detection of computer vision, speech recognition, natural language processing. We developed an artificial intelligent computer system (PX-1) with a deep neural network to analyze real-time video signals from the endoscopy station. This randomised controlled trial compared ADR between computer-assisted colonoscopy and standard colonoscopy.
Computer-assisted image analysis has the potential to further aid adenoma detection but has remained underdeveloped. A notable benefit of such a system is that no alteration of the colonoscope or procedure is necessary. Machine learning with a deep neural network has been successfully applied to many areas of science and technology, such as object recognition and detection of computer vision, speech recognition, natural language processing. We developed an artificial intelligent computer system (PX-1) with a deep neural network to analyze real-time video signals from the endoscopy station. This randomised controlled trial compared ADR between computer-assisted colonoscopy and standard colonoscopy.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: