Ignite Creation Date:
2024-05-05 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00139191
Status:
COMPLETED
Last Update Posted:
2009-11-01
First Post:
2005-08-29
Brief Title:
Study Evaluating the Correlation Between C-11 Acetate Uptake and Retention as Measured by PET and FAS in Prostate Cancer
Sponsor:
Dana-Farber Cancer Institute
Organization:
Dana-Farber Cancer Institute
Study Overview
Official Title:
A Pilot Study Evaluating the Correlation Between Carbon 11 Acetate C-11 Acetate Uptake and Retention as Measured by Positron Emission Tomography PET and Fatty Acid Synthase FAS Expression in Prostate Cancer
Status:
COMPLETED
Status Verified Date:
2009-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to understand if a new type of radiology test called positron emission tomography PET with carbon 11 acetate will help us to understand which cancers produce more of a protein called fatty acid synthase FAS
Detailed Description:
Within 4 weeks of the patients scheduled surgery they will undergo a C11 acetate PET scan This scan will be performed at the Massachusetts General Hospitals Nuclear Medicine Department and involves an intravenous injection of acetate with a radioactive tracer followed by a PET scan The scan will determine how well the tumor is taking up the acetate
Patients will also undergo a CT scan of the pelvis at the same time as the PET scan
After surgery the removed tumor will have additional testing that will look at different factors that may tell us how aggressive the tumor is and how much FAS is within the tumor FAS seems to be produced in higher amounts by prostate cancer cells than normal cells We will then try to determine if the results of the C11 acetate PET scan can tell us how much FAS is produced by prostate cancer cells
Patients will also undergo a CT scan of the pelvis at the same time as the PET scan
After surgery the removed tumor will have additional testing that will look at different factors that may tell us how aggressive the tumor is and how much FAS is within the tumor FAS seems to be produced in higher amounts by prostate cancer cells than normal cells We will then try to determine if the results of the C11 acetate PET scan can tell us how much FAS is produced by prostate cancer cells
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None