Ignite Creation Date:
2025-12-24 @ 2:55 PM
Ignite Modification Date:
2026-01-29 @ 4:58 PM
Study NCT ID:
NCT00190359
Status:
TERMINATED
Last Update Posted:
2005-09-19
First Post:
2005-09-14
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Growth Hormone and Heart Failure
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Study Overview
Official Title:
Modifications of the Growth Hormone/IGF1 Axis in Heart Failure Patients
Status:
TERMINATED
Status Verified Date:
2002-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Heart failure induces modification in several neurohormonal systems. The aim of this study is to determine if the growth hormone/IGF1 axis is modified in heart failure patients compared to healthy volunteers.
Detailed Description:
One hundred and sixty three heart failure patients were evaluated by clinical examination, echocardiography, exercise test and measurement of blood BNP. Growth hormone and IGF-1 plasma levels were determined in each patient. The same biological measurements were performed in a group of 148 healthy controls. Comparisons were performed between groups for Growth hormone plasma level, IGF-1 plasma level and Growth hormone/IGF-1 index. A correlation between the severity of heart failure and the different biological parameters was searched.
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?: