Ignite Creation Date:
2024-05-05 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 9:14 AM
Study NCT ID:
NCT00146107
Status:
COMPLETED
Last Update Posted:
2013-04-23
First Post:
2005-09-01
Brief Title:
Weight Loss and Exercise in Obese Physically Limited Older Women and Men
Sponsor:
Washington University School of Medicine
Organization:
Washington University School of Medicine
Study Overview
Official Title:
Weight Loss and Exercise in Frail Obese Elderly Subjects
Status:
COMPLETED
Status Verified Date:
2013-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine the effect of weight loss and exercise on physical function body fat and muscle mass bone strength and quality of life
Detailed Description:
Obesity causes serious medical complications and impairs quality of life Moreover in elderly persons obesity can lead to frailty by exacerbating the decline in strength endurance balance and mobility associated with aging and physical inactivity The primary objectives of the proposed research are to evaluate the independent and combined effects of weight loss and exercise on physical function body composition bone and muscle metabolism and quality of life in frail obese elderly men and women The central hypothesis is that in frail obese elderly subjects weight loss will improve physical function and quality of life while the addition of exercise will not only augment improvement in these outcomes but also attenuate the adverse effects of weight loss on bone and muscle masses To test this hypothesis 110 elderly 65-85 years old obese men and women body mass index BMI 30 kgm2 with physical frailty will be randomized to 4 treatment groups 1 control 2 10 weight loss 3 exercise training and 4 10 weight loss plus exercise training
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01AG025501 | NIH | None | httpsreporternihgovquickSearchR01AG025501 |