Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:03 AM
Study NCT ID:
NCT00002574
Status:
COMPLETED
Last Update Posted:
2013-02-05
First Post:
1999-11-01
Brief Title:
Homoharringtonine and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
Sponsor:
National Cancer Institute NCI
Organization:
National Cancer Institute NCI
Study Overview
Official Title:
PHASE II STUDY OF SIMULTANEOUS HOMOHARRINGTONINE NSC 141633 AND ALPHA INTERFERON IFN-A THERAPY IN CHRONIC MYELOGENOUS LEUKEMIA CML
Status:
COMPLETED
Status Verified Date:
2001-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Phase II trial to study the effectiveness of homoharringtonine and interferon alfa in treating patients with chronic myelogenous leukemia Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die Interferon alfa may interfere with the growth of cancer cells Combining chemotherapy with interferon alfa may kill more cancer cells
Detailed Description:
OBJECTIVES
I Determine the efficacy of homoharringtonine administered simultaneously with interferon alpha in achieving complete cytogenetic response in patients with chronic myelogenous leukemia in chronic phase
OUTLINE
Single-Agent Chemotherapy plus Biological Response Modifier Therapy Homoharringtonine HH NSC-141633 plus Interferon alfa Schering IFN-A NSC-377523
I Determine the efficacy of homoharringtonine administered simultaneously with interferon alpha in achieving complete cytogenetic response in patients with chronic myelogenous leukemia in chronic phase
OUTLINE
Single-Agent Chemotherapy plus Biological Response Modifier Therapy Homoharringtonine HH NSC-141633 plus Interferon alfa Schering IFN-A NSC-377523
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| MDA-DM-93151 | None | None | None |
| NCI-T93-0191D | None | None | None |
| CDR0000063647 | REGISTRY | PDQ Physician Data Query | None |