Ignite Creation Date:
2024-05-05 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00156221
Status:
COMPLETED
Last Update Posted:
2005-09-12
First Post:
2005-09-08
Brief Title:
MR Scanning of Very Young Children With Severe Developmental Disorders
Sponsor:
UMC Utrecht
Organization:
UMC Utrecht
Study Overview
Official Title:
MR Scanning of Very Young Children With Severe Developmental Disorders Autistic Spectrum Disorders andor Mental Retardation andor Language Disorders
Status:
COMPLETED
Status Verified Date:
2005-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The specific is to study the MR morphologic and spectroscopic brain correlates and predictors of development in children with severe developmental disorders autistic spectrum disorders andor mental retardation andor language disorders Given the frequently observed association of autism with known medical conditions particularly in cases with comorbid mental retardation and in cases with atypical autism Rutter et al 1994 Gillberg 1995 children with suspected autism or related developmental disorders will be asked to participate in an extensive state of the art laboratory work-up which includes T1 and T2 weighted MRI of the brain MRI data will be analyzed both qualitatively looking for focal abnormalities and degree of myelination and quantitatively measuring volumes of total brain cerebellum ventricles and grey and white matter For research purposes the work-up will be supplied with proton Magnetic Resonance Spectroscopy MRS of the brain This data set provides the opportunity to chart brain-behavior relationships in young children with suspected autism and related PDD cross-sectionally
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None