Ignite Creation Date:
2024-05-05 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00155532
Status:
COMPLETED
Last Update Posted:
2005-09-12
First Post:
2005-09-09
Brief Title:
Skin Denervation in Systemic Lupus Erythematosus
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To address the issues of skin denervation and its clinical and pathological correlations in systemic lupus erythematosus
Detailed Description:
To address the issues of skin denervation and its clinical and pathological correlations in lupus we will study a systemic lupus erythematosus SLE cohort by evaluating the extent of cutaneous innervation Patients are recruited from the rheumatologic clinic and various neuropsychiatric syndromes are diagnosed based on clinical judgement following detailed history taking and neurological examinations Skin biopsy with PGP 95 immunohistochemistry will be performed following established procedures after informed consent is obtained and punches of 3 mm in diameter will be taken from the lateral side of the distal leg 10 cm above the lateral malleolus Intraepidermal nerve fibre densities will be compared with results of immunological pathological psychophysical and electrophysical studies to understand the pathogenesis of peripheral neuropathy in SLE
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None