Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006059
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2000-07-05
Brief Title:
Genetic Study of Familial Epilepsy
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2003-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVES
I Determine the chromosomal regions that contain genes that raise the risk of epilepsy in families by performing genetic linkage analysis of idiopathiccryptogenic epilepsy
I Determine the chromosomal regions that contain genes that raise the risk of epilepsy in families by performing genetic linkage analysis of idiopathiccryptogenic epilepsy
Detailed Description:
PROTOCOL OUTLINE Family histories are obtained then the patients undergo an interview a neurological examination and EEG Blood specimens are also collected
Linkage analysis is performed on specimens and analysis of shared marker alleles are used to identify genomic regions likely or unlikely to contain the epilepsy genes Genotypes in family members are determined at microsatellite markers throughout the genome Markers tested include chromosomes linked to human epilepsy syndromes 6p 8p 8q 20q 21q and chromosome 3 similar to mouse epilepsy genes Linkage to markers on chromosome 10q are also tested
Patients do not receive the results of the testing and the results do not influence the type and duration of any treatment
Linkage analysis is performed on specimens and analysis of shared marker alleles are used to identify genomic regions likely or unlikely to contain the epilepsy genes Genotypes in family members are determined at microsatellite markers throughout the genome Markers tested include chromosomes linked to human epilepsy syndromes 6p 8p 8q 20q 21q and chromosome 3 similar to mouse epilepsy genes Linkage to markers on chromosome 10q are also tested
Patients do not receive the results of the testing and the results do not influence the type and duration of any treatment
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| CPMC-IRB-4465 | None | None | None |