Ignite Creation Date:
2024-05-05 @ 11:53 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00169806
Status:
RECRUITING
Last Update Posted:
2023-03-09
First Post:
2005-09-12
Brief Title:
Randalls Plaque Study Pathogenesis and Relationship to Nephrolithiasis
Sponsor:
Indiana Kidney Stone Institute
Organization:
Indiana Kidney Stone Institute
Study Overview
Official Title:
Randalls Plaques Pathogenesis and Relationship to Nephrolithiasis
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Kidney stones are very common They affect 3-5 of the population in the United States Many people are hospitalized for the treatment of kidney stones and some may die Better understanding of what causes kidney stones is useful in both the treatment and prevention of kidney stones However exactly what causes kidney stones is unknown
The most common type of kidney stones contains calcium which sometimes is attached to a part of the kidney important in producing the final urine called the papilla The investigators have noticed that persons who form kidney stones seem to have more papilla with stones attached They propose to study these areas of the papilla called Randalls plaques named after their discoverer in patients undergoing surgery for kidney stones
The most common type of kidney stones contains calcium which sometimes is attached to a part of the kidney important in producing the final urine called the papilla The investigators have noticed that persons who form kidney stones seem to have more papilla with stones attached They propose to study these areas of the papilla called Randalls plaques named after their discoverer in patients undergoing surgery for kidney stones
Detailed Description:
In order to attempt to explain the pathogenesis of renal calculi the investigators videotape and document the location and characteristics of each stone papillae and calyces One or more small papillary biopsies are taken for analysis to help determine the point of origin of the kidney stone and histological studies are undertaken to determine tissue differences amongst different types of stone formers Approximately one month after surgery metabolic studies are undertaken to further review potential causes of stone formation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None