Ignite Creation Date:
2024-05-05 @ 11:53 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00168623
Status:
UNKNOWN
Last Update Posted:
2013-11-15
First Post:
2005-09-12
Brief Title:
Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity
Sponsor:
Bandim Health Project
Organization:
Bandim Health Project
Study Overview
Official Title:
Randomised Trial of Vitamin A Supplementation Given With Routine Childhood Vaccines at National Immunisation Days
Status:
UNKNOWN
Status Verified Date:
2013-11
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Vitamin A supplementation VAS is important for the immune system and may interact with different childhood vaccinations We have hypothesized that the improved survival after VAS may depend on vitamin A amplifying the non-specific immune modulation induced by vaccinations
In the present study we used information collected in connection with a national vitamin A campaign in Guinea-Bissau during which different doses of VAS was provided together with missing doses of DTP OPV and measles vaccines We aimed to study the potential interactions between VAS and vaccine type
In the present study we used information collected in connection with a national vitamin A campaign in Guinea-Bissau during which different doses of VAS was provided together with missing doses of DTP OPV and measles vaccines We aimed to study the potential interactions between VAS and vaccine type
Detailed Description:
Vitamin A supplementation VAS acts as an adjuvant to vaccines and VAS has been shown to enhance both cellular and humoral immune responses in animals and in humans Routine childhood vaccinations have recently been shown to have important non-targeted effects on mortality ie effects that cannot be explained merely by the prevention of the targeted disease We have hypothesized that the improved survival after VAS may depend not only on the prevention of vitamin A deficiency but also on vitamin A amplifying the non-specific immune modulation induced by routine vaccinations
In the present study we used information collected in connection with a national vitamin A campaign in Guinea-Bissau during which different doses of VAS was provided together with missing doses of DTP OPV and measles vaccines We aimed to study the potential interactions between VAS and vaccine type
In the present study we used information collected in connection with a national vitamin A campaign in Guinea-Bissau during which different doses of VAS was provided together with missing doses of DTP OPV and measles vaccines We aimed to study the potential interactions between VAS and vaccine type
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 91096-03 | None | None | None |