Ignite Creation Date:
2024-05-06 @ 3:00 AM
Last Modification Date:
2024-10-26 @ 11:26 AM
Study NCT ID:
NCT02173054
Status:
COMPLETED
Last Update Posted:
2017-01-23
First Post:
2014-06-18
Brief Title:
An Efficiency of a Moisturizer Containing Licochalcone A L-carnitine and 12-decanediol With Adapalene Gel in Acne
Sponsor:
Mahidol University
Organization:
Mahidol University
Study Overview
Official Title:
An Evaluator-blind Randomized Vehicle-controlled Efficiency of Adjunctive Usage of a Moisturizer Containing Licochalcone A L-carnitine and 12-decanediol With Adapalene Gel for Improvement of Local Tolerance in Thai Acne Subjects
Status:
COMPLETED
Status Verified Date:
2016-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acne is an inflammation of sebaceous glands and follicles Applying topical treatments such as adapalene gel may cause irritant adverse effects Hence using a moisturizer is another way to protect or relieve this undesirable event Moisturizers that have anti-inflammatory property could reduce irritant effects emergent from using topical treatment and also reduce severity of acne
Research teams chose an adapalene gel to act as topical treatment for curing acne It has anti-inflammatory and comedolytic effects and has fewer side effects than other groups of topical retinoic acids However peeling skin redness skin tingling sensation or itching sensation may occur if they are continually used for a long period Thus for the purpose of studying the efficacy of moisturizer containing licochalcone A L-carnitine and 12-decanediol in reducing irritant effect of using adapalene gel Licochalcone A has anti-inflammatory effect L-carnitine decrease sebum production and 12-decanediol has anti-bacterial effect
Research teams chose an adapalene gel to act as topical treatment for curing acne It has anti-inflammatory and comedolytic effects and has fewer side effects than other groups of topical retinoic acids However peeling skin redness skin tingling sensation or itching sensation may occur if they are continually used for a long period Thus for the purpose of studying the efficacy of moisturizer containing licochalcone A L-carnitine and 12-decanediol in reducing irritant effect of using adapalene gel Licochalcone A has anti-inflammatory effect L-carnitine decrease sebum production and 12-decanediol has anti-bacterial effect
Detailed Description:
The investigators team research with patients by separate patients into 3 groups and compare among each other In the first group use only adapalene gel the second group use adapalene gel with moisturizer containing three substances mentioned above and the last group use adapalene gel with placebo moisturizer To compare outcomes among 3 groups the investigators will measure degree of redness scale oily face moist number of acne quality of life and satisfaction after using moisturizer
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None