Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00166647
Status:
WITHDRAWN
Last Update Posted:
2013-01-11
First Post:
2005-09-09
Brief Title:
Thiopurine Methyltransferase Polymorphisms Evaluation
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Study Overview
Official Title:
Evaluation of Thiopurine Methyltransferase Polymorphisms in the Hispanic Population
Status:
WITHDRAWN
Status Verified Date:
2013-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Observational Study should not be in CTgov
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study is to determine the frequency of allelic variants in TPMT in the Hispanic population and to compare the frequency in the Hispanic population with the Caucasian Population
Detailed Description:
Relatively few studies have been performed evaluating the variant allele frequencies in Spanish populations To date no studies evaluating the TPMT variant allele frequency in the Hispanic population have been reported Hispanics are a growing part of the patient population treated in the United States Characterization of the proportion of patients with variant genotypes in this population is important since Hispanic children represent a significant proportion of children being treated with thiopurines
A single 3 cc heparinized blood sample will be obtained for TPMT genotyping The sample will be obtained either simultaneously with a clinical sample at the time of an otherwise medically indicated intravenous catheter placement or scavenged from excess blood remaining following clinical laboratory testing
A single 3 cc heparinized blood sample will be obtained for TPMT genotyping The sample will be obtained either simultaneously with a clinical sample at the time of an otherwise medically indicated intravenous catheter placement or scavenged from excess blood remaining following clinical laboratory testing
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None