Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00178542
Status:
TERMINATED
Last Update Posted:
2013-05-06
First Post:
2005-09-12
Brief Title:
Change in Thrombin Generation Potential and Thromboelastography During the Menstrual Cycle
Sponsor:
The University of Texas Health Science Center Houston
Organization:
The University of Texas Health Science Center Houston
Study Overview
Official Title:
Changes in Thrombin Generation Potential and Thromboelastography During the Menstrual Cycle
Status:
TERMINATED
Status Verified Date:
2013-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Insufficient enrollment
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary objective of this study is to describe characteristics and trends for thrombin generation TG and thromboelastography TEG at 4 time points during the menstrual cycle
Detailed Description:
We propose that TG and TEG will be more sensitive than traditional coagulation assays to detect physiologic variation in hemostasis fibrinolysis and platelet activation throughout the menstrual cycle We expect that TG and TEG will better discriminate patients with vWD than traditional coagulation studies during the menstrual cycle In this study we plan to measure TG and TEG in healthy women and women with von Willebrands disorder during four phases of the menstrual cycle We will compare specific measurements of endogenous thrombin generation potential from the TG and fibrinolysis and platelet activation from the TEG with standard measures of coagulation fibrinolysis and platelet activation markers during the menstrual cycle
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None