Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00171912
Status:
COMPLETED
Last Update Posted:
2017-02-23
First Post:
2005-09-13
Brief Title:
Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes
Sponsor:
Novartis Pharmaceuticals
Organization:
Novartis
Study Overview
Official Title:
Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes
Status:
COMPLETED
Status Verified Date:
2017-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This trial is for various types of malignancies which may depend on certain enzymes tyrosine kinases for growth The objective of this study is to assess to what extent imatinib mesylate blocks these enzymes and to assess the effect on the malignancy
Detailed Description:
Condition
Diverse malignancies either associated with or thought to be associated with activated tyrosine kinase enzymes including hypereosinophilic syndrome systemic mastocytosis chronic myelomonocytic leukaemia dermatofibrosarcoma protuberans and other diseases
Not included
Patients with chronic myeloid leukemia some other types of leukemias abl-mutated some types of gastrointestinal stromal tumours c-KIT-positive some systemic mastocytosis if c-KIT D816V mutation brain prostate breast or lung cancers
Diverse malignancies either associated with or thought to be associated with activated tyrosine kinase enzymes including hypereosinophilic syndrome systemic mastocytosis chronic myelomonocytic leukaemia dermatofibrosarcoma protuberans and other diseases
Not included
Patients with chronic myeloid leukemia some other types of leukemias abl-mutated some types of gastrointestinal stromal tumours c-KIT-positive some systemic mastocytosis if c-KIT D816V mutation brain prostate breast or lung cancers
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None