Viewing Study NCT00174044



Ignite Creation Date: 2024-05-05 @ 11:55 AM
Last Modification Date: 2024-10-26 @ 9:16 AM
Study NCT ID: NCT00174044
Status: UNKNOWN
Last Update Posted: 2005-12-21
First Post: 2005-09-13

Brief Title: Control Strategies of the Locomotor System During Obstacle-Crossing in Stroke Patients
Sponsor: National Taiwan University Hospital
Organization: National Taiwan University Hospital

Study Overview

Official Title: Control Strategies of the Locomotor System During Obstacle-Crossing in Stroke Patients
Status: UNKNOWN
Status Verified Date: 2005-08
Last Known Status: RECRUITING
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Tripping over obstacles is one of the common movements in daily life and is the most frequently mentioned cause of falls in the elderly Indeed crossing obstacles is a more complex motor skill than walking and ensuring sufficient clearance of an obstacle during locomotion requires accurate movement and appropriate modifications of the swing limb However little is known about the obstacle crossing deficits that following stroke especially in good outcome and function independently strokes It is still a mystery about motor control and motor plastic of central nerve system

The purpose of the study was to observe and quantify certain characteristics of the performance of subjects following stroke with good outcome to understand the damage of central nerve system how to affect motor control The present study investigated selected spatial-temporal characteristics kinematic variables and kinetic variables of the gait pattern to define further the problems in obstacle crossing following strokes To quantify the deficits we compared results from a group of subjects with stroke with a group of healthy subjects matched for age gender and height
Detailed Description: A stroke or cerebrovascular accident is a neurological deficit that lasts beyond 24 hours It is a disruption in the blood supply to a region of the brain that causes neurological impairment According to 2003 statistical data of National Health Administration of executive organ in Taiwan a stroke is considered the second most common cause of death after cancer According to the research of the stroke incidence in Taiwan the incidence is 03 in the population over 35 years-old and the incidence increases sharply to 3 in the population over 65 years-old which is nearly 294 to 1806 people From above we know that a stroke is one of the most common neural diseases in the old population

Strokes are classified as ischemic and hemorrhagic Approximately 70-80 of all strokes are ischemic strokes including cerebrovascular thrombosis and embolism The other 10-15 are either intracerebral hemorrhage or subarachnoid hemorrhage strokes Distinctive neurological signs reflect the region of the brain involved The type and severity of neurological deficits cover a wide range and gradation of symptoms Cerebrovascular accidents frequently cause upper motor neuron syndrome Change of muscle tension unilateral hemiplegia movement un-coordination un-reciprocal movement poor movement control etc sensory deficits aphasia cognitive and behavior problems etc These deficits often left with dependence of movement function in daily life Previous studies showed that 10 of all strokes resume working 40 is slight disability 40 is server disability and 10 have to live in the medical organization forever Moderate to server disability are evaluated easily using different kinds of outcome measures to determinate the status of neurological injury and resulting disabilities which provide guideline of aggressive treatment of rehabilitation However good outcome and function independently in daily life may be showed in some strokes with mild disability by outcome measures It is not clear that the nearly normal strokes are really the same with normal group without stroke even the normal status was showed in the strokes by outcome measures It is unknown that the motor control strategies of strokes with function independently in daily life are similar to normal group indeed A recent study found that 73 of subjects with stroke fell at least once in the 6 months after being discharged from the hospital of these 10 reported falling over an obstacle Falling may be caused by the impairment after stroke or the different motor control strategy in the strokes with mild disability

In addition tripping over obstacles is one of the common movements in daily life and is the most frequently mentioned cause of falls in the elderly Lu2005 Crossing obstacles successfully and safely depend on the stability of the stance leg and maintaining a good clearance with the obstacles Indeed crossing obstacles is a more complex motor skill than walking and ensuring sufficient clearance of an obstacle during locomotion requires accurate movement and appropriate modifications of the swing limb Therefore obstacle crossing is one exercise program in diminishing disability in the rehabilitation Studies about obstacle crossing in young or old adults have been much attention However little is known about the obstacle crossing deficits that following stroke especially in good outcome and function independently strokes It is still a mystery about motor control and motor plastic of central nerve system Otherwise knowledge of the motor control strategy after stroke during obstacle-crossing is helpful for the design of fall-prevention devices and for the planning of programs for the prevention of associated injuries

The purpose of the study was to observe and quantify certain characteristics of the performance of subjects following stroke with good outcome to understand the damage of central nerve system how to affect motor control The present study investigated selected spatial-temporal characteristics kinematic variables and kinetic variables of the gait pattern to define further the problems in obstacle crossing following strokes To quantify the deficits we compared results from a group of subjects with stroke with a group of healthy subjects matched for age gender and height

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None