Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00178100
Status:
COMPLETED
Last Update Posted:
2013-08-02
First Post:
2005-09-13
Brief Title:
Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Maintenance Therapies in Late-Life Depression 2 MTLD-2
Status:
COMPLETED
Status Verified Date:
2013-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will evaluate the effectiveness of paroxetine versus interpersonal psychotherapy and a combination of the two in helping elderly patients with depression remain well and improve quality of their lives
Detailed Description:
This is primarily a study of maintenance therapies not a study of acute therapeutic efficacy in late-life major depression The study aims to identify factors that encourage maintenance of treatment gains and to identify which patients need which kinds of treatment to remain well The following questions are to be addressed
Is the probability of recurrence different among the treatment groups
What variables may be related to or predictive of differences among groups
After 1 to 2 years of maintenance therapy will patients assigned to maintenance combined treatment with both paroxetine and interpersonal psychotherapy remain well at higher rates than patients assigned to paroxetine alone interpersonal psychotherapy alone or placebo
Will the time to recurrence differ across treatment groups and what variables may be related to or predictive of time to recurrence
The major study hypothesis is that combined treatment with paroxetine and interpersonal psychotherapy will be superior to either treatment alone and to placebo in preventing recurrence of major depressive episodes in patients aged 70 and above
For information on related studies please follow these links
httpclinicaltrialsgovshowNCT00000377
httpclinicaltrialsgovshowNCT00177671
Is the probability of recurrence different among the treatment groups
What variables may be related to or predictive of differences among groups
After 1 to 2 years of maintenance therapy will patients assigned to maintenance combined treatment with both paroxetine and interpersonal psychotherapy remain well at higher rates than patients assigned to paroxetine alone interpersonal psychotherapy alone or placebo
Will the time to recurrence differ across treatment groups and what variables may be related to or predictive of time to recurrence
The major study hypothesis is that combined treatment with paroxetine and interpersonal psychotherapy will be superior to either treatment alone and to placebo in preventing recurrence of major depressive episodes in patients aged 70 and above
For information on related studies please follow these links
httpclinicaltrialsgovshowNCT00000377
httpclinicaltrialsgovshowNCT00177671
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DATR A4-GPS | None | None | None |
| 971156 | None | None | None |