Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00175968
Status:
COMPLETED
Last Update Posted:
2005-09-15
First Post:
2005-09-09
Brief Title:
Influence of Bedrest and Hypocaloric Nutrition on Endothelium-Dependent Vasoreactivity
Sponsor:
Heidelberg University
Organization:
Heidelberg University
Study Overview
Official Title:
Influence of Bed-Rest and Hypocaloric Nutrition on Endothelium-Dependent Vasoreactivity
Status:
COMPLETED
Status Verified Date:
2005-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aim of the study is to assess the impact of the factors bed rest and hypocaloric nutrition on endothelium-dependent vasoreactivity in healthy volunteers
Detailed Description:
In a randomized four-phase cross-over study the effect of simulated microgravity 13 days of bed rest energetic restriction -25 fat reduced and their combination on endothelium-dependent and -independent vasodilation will be compared with ambulatory control conditions Using venous occlusion plethysmography cumulative intraarterial dose-response curves to endothelium-dependent acetylcholine and -independent sodium nitroprusside vasodilators will be constructed in 10 healthy male volunteers before and on day 13 of each of the four intervention periods
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None