Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00176969
Status:
COMPLETED
Last Update Posted:
2014-06-02
First Post:
2005-09-12
Brief Title:
Response of Topical Capsaicin in Alopecia Areata
Sponsor:
University of Minnesota
Organization:
University of Minnesota
Study Overview
Official Title:
Perifollicular Nerves in Alopecia Areata Response to Topical Capsaicin
Status:
COMPLETED
Status Verified Date:
2014-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It has been postulated that Alopecia Areata AA is at least in part a neurologically mediated disease Research supporting this theory includes the finding that nerves surrounding the hair follicles are collapsed We want to take this research a step further and show that not only are these perifollicular nerves collapsed but that their function is also impaired
Detailed Description:
To assess the function of perifollicular scalp nerves in AA we will look at the response of these nerves to the topical medication capsaicin Under normal circumstances topical capsaicin is known to target nerves in the peripheral nervous system causing short-term release of the neuropeptide Substance P SP as well as long-term transient depletion of SP We expect the AA patients will respond abnormally to topical capsaicin treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None