Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00176553
Status:
TERMINATED
Last Update Posted:
2009-12-11
First Post:
2005-09-12
Brief Title:
A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Sponsor:
University of Medicine and Dentistry of New Jersey
Organization:
Rutgers The State University of New Jersey
Study Overview
Official Title:
A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Status:
TERMINATED
Status Verified Date:
2009-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
slow accrual
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purposes of this study are to find out whether dextromethorphan can prevent the short or long-term neurologic side effects of methotrexate and whether dextromethorphan can improve symptoms of short-term neurologic side effects if they do occur
Detailed Description:
We believe that we are beginning to understand the biological cause of the neurotoxicity that happens after treatment with methotrexate Dextromethorphan an ingredient in common cough medicines may be able to prevent andor treat this neurotoxicity We have given dextromethorphan to a small group of patients who developed severe neurologic side effects after methotrexate All had a complete recovery within one day
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| CINJ110113 | None | None | None |