Ignite Creation Date:
2024-05-06 @ 3:34 AM
Last Modification Date:
2024-10-26 @ 11:36 AM
Study NCT ID:
NCT02328755
Status:
COMPLETED
Last Update Posted:
2021-10-06
First Post:
2014-11-11
Brief Title:
Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemia
Sponsor:
University of Michigan Rogel Cancer Center
Organization:
University of Michigan Rogel Cancer Center
Study Overview
Official Title:
Targeting Cross-presentation With Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in High Risk Acute Myeloid Leukemia
Status:
COMPLETED
Status Verified Date:
2021-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This protocol is an open label single arm non-randomized phase I II clinical trial investigating the use of pegylated interferon alpha-2a peg-IFN-α Pegasys Genentech for prevention of relapse in acute myeloid leukemia AML not in remission at the time of allogeneic hematopoietic stem cell transplantation HCT
Detailed Description:
This protocol is an open label single arm non-randomized phase I II clinical trial investigating the use of pegylated interferon alpha-2a peg-IFN-α Pegasys Genentech for prevention of relapse in acute myeloid leukemia AML not in remission at the time of allogeneic hematopoietic stem cell transplantation HCT The inability to attain remission status following induction therapy for AML remains a significant problem and is associated with poor outcomes While HCT remains a curative option its activity in the setting of relapsed or refractory AML is significantly diminished due to high relapse
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| HUM00093471 | OTHER | University of Michigan | None |