Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00188370
Status:
COMPLETED
Last Update Posted:
2005-09-16
First Post:
2005-09-09
Brief Title:
Ultrasound Biomicroscopy - Apoptosis
Sponsor:
University Health Network Toronto
Organization:
University Health Network Toronto
Study Overview
Official Title:
Ultrasound Biomicroscopy for Monitoring Apoptosis in Lymphoma Melanoma and Basal Cell Carcinoma Patients During Chemotherapy or Radiation Therapy
Status:
COMPLETED
Status Verified Date:
2005-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A group of researchers at the Ontario Cancer InstitutePrincess Margaret Hospital have discovered that a very specific form of cell death apoptosis can be detected using high-frequency ultrasound imaging This type of cell death is recognized to occur in tumours in response to various different chemotherapeutic drugs and in response to radiation therapy This group of researchers has confirmed that high-frequency ultrasound can detect apoptosis in response to tumour treatments experimentally using cell culture and experimental animal systems The ultrasound approach is now being evaluated clinically in a 3-year clinical trial enrolling a target of 200 patients including Hodgkins disease and non-Hodgkins disease lymphoma patients melanoma patients and patients with basal cell carcinoma Our hope is to be able to use this type of imaging system in the future to clinically monitor the effects of therapy on tumours and rapidly detect tumours which are not responding so that changes in therapy can be made much quicker than presently possible
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None