Ignite Creation Date:
2024-05-06 @ 3:38 AM
Last Modification Date:
2024-10-26 @ 11:36 AM
Study NCT ID:
NCT02332486
Status:
UNKNOWN
Last Update Posted:
2015-01-06
First Post:
2014-12-30
Brief Title:
Based on Metabonomics Dryness Pathogen Type of OLP a Dynamic Study
Sponsor:
Heilongjiang University of Chinese Medicine
Organization:
Heilongjiang University of Chinese Medicine
Study Overview
Official Title:
Based on Metabonomics Dryness Pathogen Type of Oral Lichen Planus of Dynamic
Status:
UNKNOWN
Status Verified Date:
2015-01
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OLP
Brief Summary:
Due to the change of life style the incidence of oral cavity mucous membrane disease increasedIn this studybeen done a large number of pre-clinical practice and some experimental studies based on the application of metabolomics technology to ultra-high liquid-mass spectrometry metabolomics analyzer as the core means The metabolism of pattern recognition and combination of modern analytical techniques to measure blood and urine of patients with OLP-specific clearance of endogenous metabolitesand after the intervention of moss drink endogenous metabolites in the body as a whole group of At the same time the use of flow cytometryELISA immunohistochemistry and other modern technology research OLP patients using clean moss drink before and after treatment of local lesions and peripheral blood CD4 CD8 lymphocytesTh1 cytokines IFN-γ TNF-α Th2 cytokines IL-410 the dynamic changes From metabolomics cellular immunology inflammation mechanism perspective of local OLP lesions peripheral blood and changes in endogenous metabolites in the processin-depth study of traditional Chinese medicine to drink clean moss multi-component multi-target treatment of this disease mechanism is widely used in traditional Chinese medicine treatment of OLP provide a theoretical basis for the promotion of Chinese medicine Qingxian Yin in the oral mucosal disease in the application effectively solve clinical practice problems
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 81403441 | OTHER_GRANT | National Natural Science Foundation of China | None |