Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00187226
Status:
COMPLETED
Last Update Posted:
2023-05-31
First Post:
2005-09-13
Brief Title:
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Sponsor:
St Jude Childrens Research Hospital
Organization:
St Jude Childrens Research Hospital
Study Overview
Official Title:
A Phase II Study of Image-Guided Radiation Therapy for Pediatric CNS Tumors and Quantification of Radiation-Related CNS Effects
Status:
COMPLETED
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study was to determine if treating a limited volume of normal tissue surrounding the tumor or tumor bed using conformal radiation therapy would achieve similar rates of disease control compared to standard radiation therapy The study was also conducted to examine the effect of irradiation on neurological endocrine and cognitive function
Detailed Description:
Radiation therapy is commonly used to treat a variety of brain tumors in children including ependymoma craniopharyngioma and low- and high-grade glioma The ability of the therapy to control brain tumors in children is known to depend on the tumor type extent of resection and other clinical factors Children who received radiation therapy on this study were evaluated for treatment failure at 12 months In addition to the primary objective the study was designed to explore the association between radiation dose and volume and a variety of neurological endocrine and cognitive deficits up to 5 years after treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None