Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00183560
Status:
COMPLETED
Last Update Posted:
2015-07-01
First Post:
2005-09-13
Brief Title:
Preventing Depression Relapse With Mindfulness-Based Cognitive Therapy
Sponsor:
Centre for Addiction and Mental Health
Organization:
Centre for Addiction and Mental Health
Study Overview
Official Title:
Prevention of Relapse in Recurrent Depression With MBCT
Status:
COMPLETED
Status Verified Date:
2015-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will determine the effectiveness of mindfulness-based cognitive therapy MBCT in preventing depression relapse
Detailed Description:
Depression is a serious condition that can cause significant social and emotional problems and reduce the overall quality of life Relapses in depressive episodes are common and may result in a patients reluctance to follow a treatment regimen thus making the episode more severe Safe and effective therapies to prevent depression relapse are needed This study will compare three different approaches to determine which is most effective in preventing relapses in depressive episodes
This study will comprise 2 parts In Part 1 all participants will receive antidepressant medication for 6 months Participants whose depression symptoms do not improve will complete their study participation at the end of Part 1 Participants who respond to their regimen will be enrolled in Part 2 This part will last 18 months During Part 2 participants will be randomly assigned to one of three groups Participants in Group 1 will continue the drug regimen they began in Part 1 Participants in Group 2 will discontinue their antidepressants and attend an 8-week relapse prevention program This MBCT program is designed to help participants learn skills that can increase their awareness and change their reaction to stressful events Participants in Group 3 will have their antidepressant medication from Phase 1 switched to a placebo without their knowledge Self-report scales will be used to assess the depressive symptoms of participants at the beginning of the study at the end of Phase 1 and at the end of the study after Phase 2
This study will comprise 2 parts In Part 1 all participants will receive antidepressant medication for 6 months Participants whose depression symptoms do not improve will complete their study participation at the end of Part 1 Participants who respond to their regimen will be enrolled in Part 2 This part will last 18 months During Part 2 participants will be randomly assigned to one of three groups Participants in Group 1 will continue the drug regimen they began in Part 1 Participants in Group 2 will discontinue their antidepressants and attend an 8-week relapse prevention program This MBCT program is designed to help participants learn skills that can increase their awareness and change their reaction to stressful events Participants in Group 3 will have their antidepressant medication from Phase 1 switched to a placebo without their knowledge Self-report scales will be used to assess the depressive symptoms of participants at the beginning of the study at the end of Phase 1 and at the end of the study after Phase 2
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DSIR 83-ATP | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH066992 |
| R01MH066992 | NIH | None | None |