Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005439
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Evaluation of Childhood Blood Pressure and Lipid Screening
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2000-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To help clarify the validity reliability and utility of blood pressure BP and lipid screening in childhood
Detailed Description:
BACKGROUND
To be useful a screening program depends on an acceptable valid and reliable test and an efficacious and cost-effective intervention in the population of interest Screening children to detect those at high risk of adult hypertension or hypercholesterolemia was examined from this viewpoint Long-term studies starting in childhood have so far revealed less than optimal validity of blood pressure and serum cholesterol levels in childhood as predictors of adult levels However information was sparse regarding reliability of measurements accounting for which could improve validity The efficacy of interventions that could be widely applied in childhood had not yet been demonstrated In addition the costs of an extensive screening program and risks such as misclassification side effects and labeling needed to be evaluated The results of this study helped determine whether screening for risk factors in childhood was a useful method for preventing cardiovascular disease in adults
DESIGN NARRATIVE
The study examined the following factors that were key elements in the evaluation of screening 1 within-person variability of BP and lipid measurements ie the reliability of the test and its impact on tracking of BP and lipids from childhood to adulthood 2 calculation of predictive values sensitivity and specificity of childhood BP and lipid measurements considered as screening tests for adult values after correcting for within-person variability ie validity 3 one potentially effective intervention for BP control in children that is calcium supplementation and 4 evaluating the cost-effectiveness of screening to identify children at high risk of developing adult hypertension or hyperlipidemia
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS recor
To be useful a screening program depends on an acceptable valid and reliable test and an efficacious and cost-effective intervention in the population of interest Screening children to detect those at high risk of adult hypertension or hypercholesterolemia was examined from this viewpoint Long-term studies starting in childhood have so far revealed less than optimal validity of blood pressure and serum cholesterol levels in childhood as predictors of adult levels However information was sparse regarding reliability of measurements accounting for which could improve validity The efficacy of interventions that could be widely applied in childhood had not yet been demonstrated In addition the costs of an extensive screening program and risks such as misclassification side effects and labeling needed to be evaluated The results of this study helped determine whether screening for risk factors in childhood was a useful method for preventing cardiovascular disease in adults
DESIGN NARRATIVE
The study examined the following factors that were key elements in the evaluation of screening 1 within-person variability of BP and lipid measurements ie the reliability of the test and its impact on tracking of BP and lipids from childhood to adulthood 2 calculation of predictive values sensitivity and specificity of childhood BP and lipid measurements considered as screening tests for adult values after correcting for within-person variability ie validity 3 one potentially effective intervention for BP control in children that is calcium supplementation and 4 evaluating the cost-effectiveness of screening to identify children at high risk of developing adult hypertension or hyperlipidemia
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS recor
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R29HL048236 | NIH | None | httpsreporternihgovquickSearchR29HL048236 |