Ignite Creation Date:
2024-05-06 @ 3:50 AM
Last Modification Date:
2024-10-26 @ 11:39 AM
Study NCT ID:
NCT02381808
Status:
UNKNOWN
Last Update Posted:
2017-06-07
First Post:
2015-03-05
Brief Title:
Study on Potential Biomarkers Associated With Clinical Phenotype of EGFR-TKIs in No-small Cell Lung Cancer in China
Sponsor:
Guangdong Association of Clinical Trials
Organization:
Guangdong Association of Clinical Trials
Study Overview
Official Title:
Study on Potential Biomarkers Associated With Clinical Phenotype of EGFR-TKIs in No-small Cell Lung Cancer in China
Status:
UNKNOWN
Status Verified Date:
2017-06
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To understand 295 gene mutation mutation status include EGFR HER2 KRAS BRAF PIK3CAect by deep sequencing in Chinese patients with pulmonary adenocarcinoma and their relationships with the patients clinical features including sex age smoking history and adenocarcinoma subtype specify the predictive significance of the genes mutations for new targeted therapies in NSCLC patients and better understand the molecular mechanism drug resistance to EGFR-TKIs
Detailed Description:
This study is prospective to identify biomarkers to resistant to afatinibgefitinib and erlotinib in non-small cell lung cancer patients Mutations of whole exon of 295 gene are analysed by deep sequencing in Chinese patients with non-small cell lung cancer and their relationships with the patients clinical features including sex age smoking history and adenocarcinoma subtype specify the predictive significance of the genes mutations for new targeted therapies in NSCLC patients and better understand the molecular mechanism drug resistance to EGFR-TKIs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| BI1200250 | OTHER_GRANT | Boehringer Ingelheim | None |