Ignite Creation Date:
2024-05-05 @ 11:57 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00197457
Status:
COMPLETED
Last Update Posted:
2006-02-01
First Post:
2005-09-12
Brief Title:
Pepsinogens as the Early Marker of H Pylori Eradication
Sponsor:
Hamamatsu University
Organization:
Hamamatsu University
Study Overview
Official Title:
Serum Pepsinogens as an Early Diagnostic Marker of H Pylori Eradication
Status:
COMPLETED
Status Verified Date:
2001-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Helicobacter pylori H pylori eradication increases the serum pepsinogen PG IPG II ratio and the percentage change in PG IPG II ratios was found to be a useful marker of H pylori eradication eg the PG method We studied whether the PG method could be an early diagnostic marker of H pylori eradication even in patients persistently treated with a proton pump inhibitor Sixty-two H pylori-positive patients underwent H pylori-eradication therapy followed by treatment with a PPI to cure ulcers Serum levels of PG I and PG II were measured before at the end of and at 4 weeks after the eradication therapy At more than one month after the end of treatments 13C-urea breath test UBT was performed The cut-off values of percentage changes in PG IPG II ratios for the diagnosis of eradication of H pylori were set in proportion to PG IPG II ratios before eradication in accordance with our previous report Using the results of UBT as the standard the percentage change in serum PG IPG II ratios is useful as an early diagnostic marker for judgment of H pylori eradication irrespective of PPI treatment
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None