Ignite Creation Date:
2024-05-05 @ 11:58 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00195182
Status:
UNKNOWN
Last Update Posted:
2008-05-21
First Post:
2005-09-14
Brief Title:
Psychosocial Determinants of Medication Adherence in Hypertensive African Americans
Sponsor:
Weill Medical College of Cornell University
Organization:
Weill Medical College of Cornell University
Study Overview
Official Title:
Psychosocial Determinants of Medication Adherence in Hypertensive African Americans
Status:
UNKNOWN
Status Verified Date:
2008-05
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The specific aims for this study are
1 To examine the relationship between perceived racism and medication adherence among hypertensive African-American patients
2 To determine if psychological stress and depression mediate the relationship between perceived racism and medication adherence
1 To examine the relationship between perceived racism and medication adherence among hypertensive African-American patients
2 To determine if psychological stress and depression mediate the relationship between perceived racism and medication adherence
Detailed Description:
Achieving and maintaining recommended blood pressure goals in hypertensive African Americans is paramount to addressing racial disparities in hypertension-related morbidity and mortality Because antihypertensive therapy is the cornerstone of hypertension management good medication adherence is the key to adequate blood pressure control Successful approaches to racial disparities must address how to increase adherence to anti-hypertensive medications
Adherence to anti-hypertensive medications is likely multifactorial and not solely related to SES or access to medical care Psychosocial factors such as stress and depression have been implicated as important determinants of medication adherence However little is known about how other psychosocial factors such as perceived racism impact anti-hypertensive medication adherence Understanding these relationships may assist in the development of targeted strategies to achieve good medication adherence in hypertensive patients
The objective is to understand the relationships between perceived racism and medication adherence while examining the role of depression psychological stress and self-efficacy in a population of hypertensive African-American patients 262 African American adult hypertensive patients will be recruited from an urban academic general medicine practice Baseline data collection will include assessments of demographics and socioeconomic status clinical history and hypertension characteristics depressive symptoms perceived stress and medication adherence Patients will be followed for 1 year when final evaluations will take place including assessment of hypertension stress depression medication adherence and level of perceived racism measured by a validated instrument The primary outcome is the change in medication adherence scores from baseline to 12 months Statistical models will be developed to determine if level of perceived racism is associated with medication adherence and whether stress and depression play a role in this relationship
Adherence to anti-hypertensive medications is likely multifactorial and not solely related to SES or access to medical care Psychosocial factors such as stress and depression have been implicated as important determinants of medication adherence However little is known about how other psychosocial factors such as perceived racism impact anti-hypertensive medication adherence Understanding these relationships may assist in the development of targeted strategies to achieve good medication adherence in hypertensive patients
The objective is to understand the relationships between perceived racism and medication adherence while examining the role of depression psychological stress and self-efficacy in a population of hypertensive African-American patients 262 African American adult hypertensive patients will be recruited from an urban academic general medicine practice Baseline data collection will include assessments of demographics and socioeconomic status clinical history and hypertension characteristics depressive symptoms perceived stress and medication adherence Patients will be followed for 1 year when final evaluations will take place including assessment of hypertension stress depression medication adherence and level of perceived racism measured by a validated instrument The primary outcome is the change in medication adherence scores from baseline to 12 months Statistical models will be developed to determine if level of perceived racism is associated with medication adherence and whether stress and depression play a role in this relationship
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None