Ignite Creation Date:
2024-05-05 @ 10:22 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006307
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-09-28
Brief Title:
Epidemiology of Body Mass Index Rebound
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2008-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To investigate the relationship between obesity body mass index BMI rebound body composition changes associated factors eg diet physical activity and cardiovascular risk factor status in a longitudinal study of young children age three at the beginning of the study
Detailed Description:
BACKGROUND
Obesity is the most prevalent nutritional problem in the United States It appears that both the prevalence and severity of obesity have been increasing in recent years Obesity often begins in childhood and has a number of severe sequelae including non insulin dependent diabetes mellitus and cardiovascular disease Unfortunately obesity is very resistant to treatment This places a premium on prevention However the identification of clinically useful predictors of obesity which are present prior to the onset of excess weight gain has been problematic Recently it has been shown that the timing of body mass index BMI rebound may be a predictor of future obesity BMI increases during the first year of life It then declines until it reaches a minimum value during childhood and subsequently increases into adolescence and adulthood The nadir of BMI is called BMI rebound Studies have shown that BMI rebound at a young age is associated with increased risk of obesity later in life Currently very little is known about the epidemiology of BMI rebound
DESIGN NARRATIVE
The investigation is a cohort study designed to follow 320 children from age three to age seven years The study design will be a longitudinal one in which the children will be followed for a period of four years during which repeat measurements of body composition diet and physical activity will be made every four months Parental height and weight data will be collected in addition to family health history parental smoking and alcohol intake
Obesity is the most prevalent nutritional problem in the United States It appears that both the prevalence and severity of obesity have been increasing in recent years Obesity often begins in childhood and has a number of severe sequelae including non insulin dependent diabetes mellitus and cardiovascular disease Unfortunately obesity is very resistant to treatment This places a premium on prevention However the identification of clinically useful predictors of obesity which are present prior to the onset of excess weight gain has been problematic Recently it has been shown that the timing of body mass index BMI rebound may be a predictor of future obesity BMI increases during the first year of life It then declines until it reaches a minimum value during childhood and subsequently increases into adolescence and adulthood The nadir of BMI is called BMI rebound Studies have shown that BMI rebound at a young age is associated with increased risk of obesity later in life Currently very little is known about the epidemiology of BMI rebound
DESIGN NARRATIVE
The investigation is a cohort study designed to follow 320 children from age three to age seven years The study design will be a longitudinal one in which the children will be followed for a period of four years during which repeat measurements of body composition diet and physical activity will be made every four months Parental height and weight data will be collected in addition to family health history parental smoking and alcohol intake
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL064022 | NIH | None | httpsreporternihgovquickSearchR01HL064022 |