Ignite Creation Date:
2024-05-06 @ 7:12 AM
Last Modification Date:
2024-10-26 @ 11:46 AM
Study NCT ID:
NCT02497833
Status:
COMPLETED
Last Update Posted:
2015-07-15
First Post:
2015-07-08
Brief Title:
Retinoic Acid Supplementation and Subjects With Hypercholesterolemia
Sponsor:
Sun Yat-sen University
Organization:
Sun Yat-sen University
Study Overview
Official Title:
Effect of Retinoic Acid Supplementation on the HDL-Associated Paraoxonase 1 Activity in Subjects With Hypercholesterolemia A Randomized Double-Blinded Placebo-Controlled Trial
Status:
COMPLETED
Status Verified Date:
2015-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the study is to investigate the effects of retinoic acid on the HDL-PON1 activity and cholesterol efflux capacity in hypercholesterolemic subjects
Detailed Description:
Paraoxonase 1 PON1 an enzyme associated with high-density lipoprotein is reported to have antioxidant and cardioprotective properties And all-trans-retinoic acid revealed the ameliorating atherosclerosis effects in many reportsThere maybe some correlations between retinoic acid and PON1 activity and the study aim to prove it
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None