Ignite Creation Date:
2024-05-05 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00204932
Status:
COMPLETED
Last Update Posted:
2018-07-17
First Post:
2005-09-12
Brief Title:
Effects of CLA Supplements on Body Weight and Fat Oxidation
Sponsor:
University of Wisconsin Madison
Organization:
University of Wisconsin Madison
Study Overview
Official Title:
Effects of CLA Supplements on Body Weight and Fat Oxidation
Status:
COMPLETED
Status Verified Date:
2018-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Conjugated linoleic acid CLA is form of fat found in dairy foods beef and other natural sources When given to small animals decreases of body fat have been noted Although weight loss is the best treatment for overweight and obesity it is difficult to maintain the loss in the long term Because of this treatment emphasis has turned to small weight losses obtained through non-restrictive diets and prevention of weight regain This is a study to determine if 6 months of consumption a purified form of CLA will result in greater loss of body fat than control and to determine whether CLA consumption increases total fat oxidation which would help explain why the weight loss occurs
Detailed Description:
Subjects were screened and then underwent baseline evaluation The substudy evaluation measured 24-h energy expenditure and substrate utilization by using a whole-room indirect calorimeter Dietary fat oxidation was measured by mixing 1-13Coleate and D31-palmitate into a breakfast meal and then collecting breath carbon dioxide and urine to measure the end products of oxidation Subjects were then provided either 4 gd of 78 active CLA isomers 32 gd 392 cis-9trans-11 and 385 trans-10cis-12 or 4 gd of safflower oil placebo as 1-g gel capsule supplements The baseline evaluations were repeated 6 mo later
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None