Official Title: Rhinovirus Infection and Asthma in Childhood and Adolescents
Status: COMPLETED
Status Verified Date: 2019-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: COAST
Brief Summary: Although asthma is likely to be a heterogeneous disease or syndrome three factors andor events repetitively emerge for their ability to significantly influence asthma inception in the first decade of life immune response aberrations which appear to be defined best by the concept of cytokine dysregulation lower respiratory tract infections in particular RSV and some form of gene by environment interaction that needs to occur at a critical time period in the development of the immune system or the lung It remains to be firmly established however how any one or all of these factors either independently or interactively influence the development of childhood asthma Thus our efforts to determine and define the importance of these three factors to asthma pathogenesis are the focus and goal of this current grant application
Detailed Description: No more description necessary