Ignite Creation Date:
2024-05-05 @ 10:22 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001840
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Evaluation of Treated and Untreated Stroke
Sponsor:
National Institutes of Health Clinical Center CC
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Evaluation of Treated and Untreated Stroke
Status:
COMPLETED
Status Verified Date:
2001-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This project will investigate the evolution of treated and untreated stroke in patients recruited from the collaborative brain stroke program between NINDS CC and Suburban Hospital The study will use anatomical and functional imaging techniques with emphasis on the acute and subacute stage less than one month of the disease
As the availability of new therapeutic options for the management of acute brain stroke increases the need to define the evolution of the disease becomes paramount particularly as therapeutic windows defined by known and perhaps yet undiscovered parameters may exist Defining these parameters will be based on state-of-the-art imaging technology with the potential of clarifying the division between ischemia reversible damage and infarction irreversible Measures of lesion size and distribution along with vascular morphology diffusion perfusion flow-related and metabolic measures will be obtained over time We foresee these measurements will significantly develop our understanding of cerebral ischemia and introduce diagnostic and quantitative tools to guide therapy and measure its efficacy
As the availability of new therapeutic options for the management of acute brain stroke increases the need to define the evolution of the disease becomes paramount particularly as therapeutic windows defined by known and perhaps yet undiscovered parameters may exist Defining these parameters will be based on state-of-the-art imaging technology with the potential of clarifying the division between ischemia reversible damage and infarction irreversible Measures of lesion size and distribution along with vascular morphology diffusion perfusion flow-related and metabolic measures will be obtained over time We foresee these measurements will significantly develop our understanding of cerebral ischemia and introduce diagnostic and quantitative tools to guide therapy and measure its efficacy
Detailed Description:
This project will investigate the evolution of treated and untreated stroke in patients recruited from the collaborative brain stroke program between NINDS CC and Suburban Hospital The study will use anatomical and functional imaging techniques with emphasis on the acute and subacute stage less than one month of the disease
As the availability of new therapeutic options for the management of acute brain stroke increases the need to define the evolution of the disease becomes paramount particularly as therapeutic windows defined by known and perhaps yet undiscovered parameters may exist Defining these parameters will be based on state-of-the-art imaging technology with the potential of clarifying the division between ischemia reversible damage and infarction irreversible Measures of lesion size and distribution along with vascular morphology diffusion perfusion flow-related and metabolic measures will be obtained over time We foresee these measurements will significantly improve our understanding of cerebral ischemia and introduce diagnostic and quantitative tools to guide therapy and measure its efficacy
As the availability of new therapeutic options for the management of acute brain stroke increases the need to define the evolution of the disease becomes paramount particularly as therapeutic windows defined by known and perhaps yet undiscovered parameters may exist Defining these parameters will be based on state-of-the-art imaging technology with the potential of clarifying the division between ischemia reversible damage and infarction irreversible Measures of lesion size and distribution along with vascular morphology diffusion perfusion flow-related and metabolic measures will be obtained over time We foresee these measurements will significantly improve our understanding of cerebral ischemia and introduce diagnostic and quantitative tools to guide therapy and measure its efficacy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 99-CC-0041 | None | None | None |