Ignite Creation Date:
2024-05-05 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00203788
Status:
COMPLETED
Last Update Posted:
2013-07-30
First Post:
2005-09-14
Brief Title:
Improving Work Outcome in People With Recent-onset Schizophrenia
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
Developmental Processes in Schizophrenic Disorders Improving and Predicting Work Outcome in Recent-Onset Schizophrenia
Status:
COMPLETED
Status Verified Date:
2008-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will determine the effectiveness of combining antipsychotic medication with Individual Placement and Support IPS and group training with the Workplace Fundamentals Module or Brokered Vocational Rehabilitation in facilitating the search for appropriate work or schooling and maintaining work or school activities in people with recent-onset schizophrenia
Detailed Description:
The purpose of this protocol is to test in recent-onset schizophrenia the efficacy of a rehabilitative intervention that is designed to enhance the search for appropriate work or schooling and to increase ability to maintain work or school activities more successfully Predictors of work outcome are being assessed in the context of this work rehabilitation and treatment with the second-generation antipsychotic medication risperidone
The Developmental Processes in Schizophrenic Disorders project involves an ongoing series of longitudinal follow-through studies of individuals with a recent onset of schizophrenia The current protocol focuses particularly on processes affecting work outcome in this initial period after onset of schizophrenia drawing on findings that link cognitive deficits in schizophrenia to functional outcome The protocol is determining the effects on work outcome of a rehabilitative intervention designed to enhance search for appropriate work or schooling and to increase ability to maintain work or school activities more successfully All entering patients are placed on a common antipsychotic medication oral risperidone and are provided clinical treatment by a psychiatrist and a case manager Participating patients are randomly assigned to a combination of Individual Placement and Support IPS and group training with the Workplace Fundamentals Module or to a Brokered Vocational Rehabilitation Model
The protocol is examining the predictors of level of work functioning attained in the context of the work-focused intervention and maintenance on risperidone Potential neurocognitive and environmental predictors of work and social functioning and clinical course are being examined Aspects of early perceptual processing allocation of attention working memory secondary verbal memory and conceptual flexibility that are implicated as influences on functional outcome are assessed as are potential stresses and supportive influences in the environment
The Developmental Processes in Schizophrenic Disorders project involves an ongoing series of longitudinal follow-through studies of individuals with a recent onset of schizophrenia The current protocol focuses particularly on processes affecting work outcome in this initial period after onset of schizophrenia drawing on findings that link cognitive deficits in schizophrenia to functional outcome The protocol is determining the effects on work outcome of a rehabilitative intervention designed to enhance search for appropriate work or schooling and to increase ability to maintain work or school activities more successfully All entering patients are placed on a common antipsychotic medication oral risperidone and are provided clinical treatment by a psychiatrist and a case manager Participating patients are randomly assigned to a combination of Individual Placement and Support IPS and group training with the Workplace Fundamentals Module or to a Brokered Vocational Rehabilitation Model
The protocol is examining the predictors of level of work functioning attained in the context of the work-focused intervention and maintenance on risperidone Potential neurocognitive and environmental predictors of work and social functioning and clinical course are being examined Aspects of early perceptual processing allocation of attention working memory secondary verbal memory and conceptual flexibility that are implicated as influences on functional outcome are assessed as are potential stresses and supportive influences in the environment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DAHBR AD-P | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH037705 |
| R01MH037705 | NIH | None | None |
| Janssen RIS-USA-67 | None | None | None |