Ignite Creation Date:
2024-05-05 @ 12:00 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00208962
Status:
COMPLETED
Last Update Posted:
2014-08-12
First Post:
2005-09-13
Brief Title:
Allogeneic Cell Therapy for Adults With Hematologic Malignancies
Sponsor:
Emory University
Organization:
Emory University
Study Overview
Official Title:
Allogeneic Cell Therapy for Adults With Hematologic Malignancies
Status:
COMPLETED
Status Verified Date:
2014-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a research study involving the treatment of leukemia or lymphoma lymph gland cancer in adults who have leukemia or lymphoma that is unlikely to be cured with regular anticancer drugs or radiation treatments
Detailed Description:
This is a research study involving the treatment of leukemia or lymphoma lymph gland cancer in adults who have leukemia or lymphoma that is unlikely to be cured with regular anticancer drugs or radiation treatments Intensive treatment with high doses of chemotherapy followed by a bone marrow transplant BMT from an HLA-tissue-type matched related donor would provide the best chance for cure of this leukemia or lymphoma However the success of BMT from relatives is limited in patients who are older than 50 years andor have organ dysfunction by substantial complications due to the high dose chemotherapy related toxicity graft-versus- host disease GVHD and relapse Patients eligible for this study have an HLA matched sibling but a BMT from the sibling would carry a high risk for severe side effects due to the patients age andor organ dysfunction
Researchers are evaluating a new treatment for adult patients with leukemia and lymphoma which involves regular dose chemotherapy and blood stem cell transplantation from an HLA-matched relative with injections of donor immune cells a type of white blood cells given if you later relapse In this study the safety and feasibility of this treatment strategy are being investigated
Researchers are evaluating a new treatment for adult patients with leukemia and lymphoma which involves regular dose chemotherapy and blood stem cell transplantation from an HLA-matched relative with injections of donor immune cells a type of white blood cells given if you later relapse In this study the safety and feasibility of this treatment strategy are being investigated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None