Ignite Creation Date:
2024-05-05 @ 12:00 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00208000
Status:
UNKNOWN
Last Update Posted:
2010-11-29
First Post:
2005-09-16
Brief Title:
A Clinical Double Blind Randomized Study of the Efficacy of Hyperuricemia Treatment With Anserine Product
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2005-09
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hyperuricemia is a common metabolic disorderThe Yaizu Suisankagaku Industry Company have developed industrial production named Marine Active was able to offer anti-fatigue activity by animal trial data Human clinical trials showed reduced creatine phosphokinase activity and a sero-uric acid reduction activity was also observed So we are committed to design the clinical randomized double blind study about hyperuricemia management with Marine Active All these efforts are hoped to find a novel method to manage hyperuricemia
Detailed Description:
Hyperuricemia is a common metabolic disorder It can result from a decreased renal uric acid excretion increased urate production or both The classical association with clinical gout is well-known The principal indications for uric acid-lowering therapy including allopurinol probenecid and sulfinpyrazone are the patients with gout history macroscopic subcutaneous tophi frequent attacks of gouty arthritis or a documented state of uric acid overproduction Hyperuricemia without gout attack is not an indication for treatmentHowever hyperuricemia is often associated with other cardiovascular disease risk factors such as obese hyperlipidemia glucose intolerance and hypertension It is known a symptom of syndrome X also known as multiple risk factor clustering syndrome Diet control is the only way to control serum uric acid level but always it is not enough So how to management hyperuricemia is important and is a potential managementHistidine-containing dipeptides such as Anserine and Carnosine have been studied extensively in recent years These dipeptides were shown to be effective in acting as buffering agents against protons developed during anaerobic exercise Anserine and Carnosine also have strong anti-oxidant activity anti-cancer activity immuno-response modulation fat reduction and enhanced wound healing functions The Yaizu Suisankagaku Industry Company have developed industrial production process to extract and purify the dipeptides from Bonito and Tuna The extract named Marine Active was able to offer anti-fatigue activity by animal trial data Human clinical trials showed reduced creatine phosphokinase activity and a sero-uric acid reduction activity was also observed So we are committed to design the clinical randomized double blind study about hyperuricemia management with Marine Active All these efforts are hoped to find a novel method to manage hyperuricemia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None