Ignite Creation Date:
2024-05-05 @ 12:00 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00200928
Status:
COMPLETED
Last Update Posted:
2006-04-04
First Post:
2005-09-12
Brief Title:
Asthma a Disease Due to a Lack of Bacterial Infections in Childhood
Sponsor:
The Netherlands Asthma Foundation
Organization:
The Netherlands Asthma Foundation
Study Overview
Official Title:
Asthma a Disease Due to a Lack of Bacterial Infections in Childhood
Status:
COMPLETED
Status Verified Date:
2006-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The degree of TH1-skewing by mycobacteria is controlles by NRAMP1 gene polymorphisms and related to the degree of inhibition of TH2-mediated disease
Detailed Description:
A randomised single blinded intervention study in high-risk newborns vaccinated at the age of 6 weeks with BCG or placebo
Inclusion high-risk was defined as either a mother or a father and a sibling with present or past atopic disease
Exclusion maternal infection in the last week of pregnancy the use of immunomodulatory drugs or antibiotics during pregnancy mother the use of antibiotics directly post-partum newborn
Inclusion high-risk was defined as either a mother or a father and a sibling with present or past atopic disease
Exclusion maternal infection in the last week of pregnancy the use of immunomodulatory drugs or antibiotics during pregnancy mother the use of antibiotics directly post-partum newborn
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None