Ignite Creation Date:
2024-05-05 @ 12:01 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00213876
Status:
COMPLETED
Last Update Posted:
2011-08-30
First Post:
2005-09-13
Brief Title:
Research of Molecular and Metabolic Markers in Oligodendrogliomas Comparatively to Other Brain Tumours
Sponsor:
University Hospital Strasbourg France
Organization:
University Hospital Strasbourg France
Study Overview
Official Title:
Research of Molecular and Metabolic Diagnostic Markers in Oligodendrogliomas A and B Comparatively
Status:
COMPLETED
Status Verified Date:
2011-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
At present diagnosis of oligodendroglioma is made on histological and radiographic criteria in the French Mayo-Ste Anne classification The less frequent grade A oligodendrogliomas are characterized by no vascular contrast on RMN evaluation comparatively to grade B forms This benign histological subtype relapses in few cases with a more aggressive histology To determine these relapsed cases at diagnosis a collection of tumour begun in February 2004 Then our study was designed to identify diagnostic molecular and metabolic markers that could eventually be used as a signature characterising grade A versus grade B oligodendrogliomas The molecular analysis will use genomic techniques like allelotyping study quantitative real-time PCR gene sequencing serial analysis of genomic expression and immunohistochemistry since the metabolic study will be the spectroscopic examination of in vivo tumour This study will include paediatric and adult patients followed for oligodendrogliomas medulloblastomas and gliomas to compare the different tumour signatures All these results will be correlated to survival and clinical features
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None