Ignite Creation Date:
2024-05-05 @ 12:01 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00216814
Status:
TERMINATED
Last Update Posted:
2008-04-22
First Post:
2005-09-19
Brief Title:
Antiangiogenic Effects of BCG on Urinary Concentration of Angiogenic Factors
Sponsor:
Lawson Health Research Institute
Organization:
Lawson Health Research Institute
Study Overview
Official Title:
Intravesically Administered BCG May Have Antiangiogenic Effects on Urinary Concentrations of Basic Fibroblast Growth Factor bFGF Vascular Endothelial Growth Factor VEGF and Interleukin IL-8
Status:
TERMINATED
Status Verified Date:
2008-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
No funding and data was not appropriate to consider continuing
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To determine if there is an association between basic fibroblast growth factorvascular endothelial growth factor and interleukin levels and a patients response to BCG treatment as standard treatmentin the urine of patients with superficial TCC To determine if the levels of these angiogenic factors can predict response to BCG disease recurrence progression risk factors
Detailed Description:
200 patients that are candidates for intravesical BCG therapy and 20 control patients with no history of malignancy will be enrolled The study group wol be asked to provide a urine sample just prior to receiving their first BCG treatmentweek 1 and just prior to receiving their last week 6 BCG treatment The control patients will provide one urine sample only Samples will be analysed by enzyme-linked immunosorbant assayELISA clinical data will be reviewed on tumor stage and grade prior to BCG timme to recurrence tumor stage and grade of recurrence time to disease progression and death cause of death and total follow-up time
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 10050E | None | None | None |