Ignite Creation Date:
2024-05-06 @ 8:18 AM
Last Modification Date:
2024-10-26 @ 11:59 AM
Study NCT ID:
NCT02715869
Status:
COMPLETED
Last Update Posted:
2017-12-12
First Post:
2016-03-17
Brief Title:
Impact of Variable Types of Preconditioning Upon the Inotrope Score in Adult Patients Undergoing Cardiac Surgery
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Impact of Variable Types of Preconditioning Upon the Inotrope Score in Adult Patients Undergoing Cardiac Surgery
Status:
COMPLETED
Status Verified Date:
2017-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Preconditioning PC of the heart occurs when brief exposure to a stimulus protects the heart from subsequent ischemia PC stimulus may be ischemic pharmacologic or Physical
Detailed Description:
Preconditioning PC of the heart occurs when brief exposure to a stimulus protects the heart from subsequent ischemia PC stimulus may be ischemic pharmacologic or Physical
Pharmacological PC may be induced by variable agents eg Sevoflurane isoflorane opioids etc
Ischemic PC includes local remote and the idea is temporary interruption of blood supply to the organ so that liberation of protective mediators occurs The liberated mediators have favorable effects not only upon the myocardium but it extend to protect other organs against inflammatory activation ischemia reperfusion injury
Inotropic score IS is already an evident predictor of postoperative cardiac morbidity and mortality
Aim of the work
Is to validate the impact of Sevoflurane versus ischemic Sevoflurane PC upon postoperative inotropic score in adult patient undergoing open heart surgery
Pharmacological PC may be induced by variable agents eg Sevoflurane isoflorane opioids etc
Ischemic PC includes local remote and the idea is temporary interruption of blood supply to the organ so that liberation of protective mediators occurs The liberated mediators have favorable effects not only upon the myocardium but it extend to protect other organs against inflammatory activation ischemia reperfusion injury
Inotropic score IS is already an evident predictor of postoperative cardiac morbidity and mortality
Aim of the work
Is to validate the impact of Sevoflurane versus ischemic Sevoflurane PC upon postoperative inotropic score in adult patient undergoing open heart surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None